UFC on ABC 3: Ortega vs. Rodríguez was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on July 16, 2022, at UBS Arena in Elmont, New York in the United States. A featherweight bout between former UFC Featherweight Championship challenger Brian Ortega and The Ultimate Fighter: Latin America featherweight winner Yair Rodríguez headlined the event.

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