When a bag filled with money goes missing from a casino, the Hitman (Chris O'Donnell) must retrieve it. While he tracks the stash down, the bag changes hands numerous times, finding its way to the Drifter (Jeremy Davies) and the Waitress (Rachael Leigh Cook), among others. As the bag's journey continues, more characters, including the Cop (Michael Rapaport) and the Sheriff (Keith David), get drawn into the winding crime tale, and the search becomes increasingly desperate.

"Money. Murder. Betrayal. It's all in the bag."